Registry data show that about 93% of total knee replacements are still functioning at 15 years, 90% at 20 years, and 82% at 25 years (Evans et al., The Lancet, 2019), but failure can occur for several reasons:
Loosening
The bond between the implant and bone can weaken over time, particularly if microscopic wear particles trigger an inflammatory response that erodes the surrounding bone (osteolysis). A loose implant causes pain, instability, and progressive bone loss.
Instability
A knee replacement depends on balanced soft tissues and properly sized components for stability. If the ligaments are insufficient or the components are not well-balanced, the knee may feel loose or "give way." Chronic instability limits function and confidence.
Stiffness
Some knees develop excessive scar tissue (arthrofibrosis) after replacement, resulting in a stiff joint with limited range of motion. When physical therapy and manipulation under anesthesia are not effective, surgical revision may be needed.
Infection
Prosthetic joint infection is a serious complication that often requires surgical intervention. Bacteria adhere to the implant surface and form biofilm, making antibiotic treatment alone insufficient in most cases.
Wear
The polyethylene (plastic) bearing surface between the metal components wears over time. Modern plastics are highly durable, but older implants or those under heavy use may wear through, causing pain and instability.
Periprosthetic Fracture
A fracture around the knee implant can occur after a fall or from weakened bone. Depending on the fracture pattern and implant stability, revision of one or both components may be required.
Malalignment
A knee replacement placed in poor alignment can cause abnormal wear, pain, and accelerated failure. Robotic-assisted technology in primary surgery aims to reduce this problem, but revision may be needed when malalignment is the cause of a failed replacement.